Prefabricated, bio-absorbable implantable mesh embedded with TheraSeed® or AgX100® for permanent implantation

Selected Tumor Characteristics and types1,2

  • Localized or unresectable with low to moderate radiosensitivity
  • Recurrent
  • Residual following external beam radiation or excision
    of primary tumor
  • Superficial, intrathoracic, intra-abdominal
  • Lung, Pancreas, and Head & Neck
  • Deep Cavity Soft Tissue Sarcoma3
    • Chest
    • Abdomen
    • Pelvis
    • Retroperitoneum
    • Deep truncal locations

Provides a flexible brachytherapy platform that may be contoured to implant surfaces

  • Low energy brachytherapy seeds with rapid dose fall off to minimize dose to normal structures
  • TheraSeed – Pd 103: 16.9 day half life; 20-23 keV principle energy
  • AgX100 – I 125: 59.4 day half life; 27-35 keV principle energy
  • An alternative delivery system for radiotherapy to tumor beds3
  • May be suitable for anticipated close surgical margins and where other treatment options are limited3
  • May be advantageous when the target volume is irregular and complex and critical normal structures are adjacent to the tumor implant4
  • Permanent implant allows for a higher total radiation dose to be delivered to the target volume4


  • Prefabricated per a physician’s specification
  • Bio-absorbable 90/10 (glycolide/L-lactide) mesh consists of:
    • 1 to 6 rows of flexible bio-absorbable 90/10 (glycolide/L-lactide) braided suture strands
      • Each strand row embedded with (10) TheraSeed or (10) AgX100 seeds
      • Seeds are spaced at a fixed distance of 1 cm center to center of seed
      • Strand rows are spaced at 1 cm distance
      • Bio-absorption occurs in 56-70 days
  • Packaging
    • Sterile
    • Single mesh per sterile, shielded container
    • Shielded tray suitable for sterile field

Download PDF: Theragenics TheraMesh


1Theragenics, TheraSeed Instructions for Use, Buford, GA, 2016
2Theragenics, AgX100 Instructions for Use, Buford, GA, 2016
3Fairweather M, Wang, J, Devlin P, et al. Safety and efficacy of radiation dose delivered via Iodine-125 brachytherapy mesh implantation for deep cavity sarcomas. Ann Surg Oncol (2015) 22:1455–1463
4Devlin P, (ed), Brachytherapy Applications and Techniques, Second Edition, Demos Medical Publishing, LLC, New York, NY (2016)